8.1 IMMUNOSUPPRESSIVE DRUGS

Adequate resources and specialist oversight are a prerequisite

for the introduction of this class of drugs.

¤azathioprine (2) tablet, 50 mg

powder for injection, 100 mg

(as sodium salt) in vial

¤ciclosporin (2) capsule, 25 mg

(for organ transplantation)

concentrate for injection,

50 mg/ml in 1-ml ampoule

8.2 CYTOTOXIC DRUGS

Adequate resources and specialist oversight are a prerequisite

for the introduction of this class of drugs.

asparaginase (2) powder for injection,

10 000 IU in vial

bleomycin (2) powder for injection, 15 mg

(as sulfate) in vial

calcium folinate (2) tablet, 15 mg

injection, 3 mg/ml in 10-ml ampoule

chlorambucil (2) tablet, 2 mg

chlormethine (2) powder for injection, 10 mg

(hydrochloride) in vial

¤ Example of a therapeutic group. Various drugs can serve as alternatives.

Essential Drugs

cisplatin (2) powder for injection,

10 mg, 50 mg in vial

cyclophosphamide (2) tablet, 25 mg

powder for injection,

500 mg in vial

cytarabine (2) powder for injection,

100 mg in vial

dacarbazine (2) powder for injection,

100 mg in vial

daunorubicin (2) powder for injection,

50 mg (as hydrochloride) in vial

dactinomycin (2) powder for injection

500 µg in vial

¤doxorubicin (2) powder for injection, 10 mg,

50 mg (hydrochloride) in vial

etoposide (2) capsule, 100 mg

injection, 20 mg/ml in 5-ml ampoule

fluorouracil (2) injection, 50 mg/ml

in 5-ml ampoule

levamisole (2) tablet, 50 mg

(as hydrochloride)

mercaptopurine (2) tablet, 50 mg

methotrexate (2) tablet, 2.5 mg (as sodium salt)

powder for injection, 50 mg

(as sodium salt) in vial

procarbazine capsule, 50 mg (as hydrochloride)

vinblastine (2) powder for injection,

10 mg (sulfate) in vial

vincristine (2) powder for injection,

1 mg, 5 mg (sulfate) in vial

8.3 HORMONES AND ANTIHORMONES

¤prednisolone tablet, 5 mg

powder for injection, 20 mg,

25 mg (as sodium phosphate or

sodium succinate) in vial

tamoxifen tablet, 10 mg, 20 mg (as citrate)

8.4 DRUGS USED IN PALLIATIVE CARE

The WHO Expert Committee on Essential Drugs recommended

that all the drugs mentioned in the WHO publication

Cancer Pain Relief: with a Guide to Opioid Availability,

2nd edition, be considered essential. The drugs

are included in the relevant sections of the model list

according to their therapeutic use, e.g. analgesics.